Erythrocyte glutathione S-transferase deficiency and hemolytic anemia

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Erythrocyte glutathione S-transferase deficiency and hemolytic anemia.

A patient with unexplained erythrocyte glutathione-S-transferase (GST) deficiency has been detected among 513 unrelated persons with hemolytic anemia. An otherwise healthy adult male, the deficient individual had a mild hemolytic anemia with splenomegaly, indirect hyperbilirubinemia, and cholelithiasis. Because he was adopted and childless, the hereditary nature of the defect could not be estab...

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Overexpression of erythrocyte glutathione S-transferase in uremia and dialysis.

BACKGROUND Overexpression of glutathione S-transferase (GST; EC 2.5. 1.18) has been documented in the erythrocytes of patients with chronic renal failure, and this event may well be of relevance from a clinical standpoint. In fact, it could serve as a marker of uremic toxicity overall, which can contribute to impair the function and survival of the erythrocytes. However, the biochemical details...

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Erythrocyte glutathione S-transferase. Electrophoretic identification of two enzyme forms.

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Glutathione S transferase deficiency and passive smoking increase childhood asthma.

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ژورنال

عنوان ژورنال: Blood

سال: 1988

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v72.1.73.bloodjournal72173